In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy.

To evaluate liposome formulations for use as intracellular sustained-release drug depots, we have compared the uptake and degradation in rat liver and spleen of liposomes of various compositions, containing as their bulk phospholipid an ether-linked phospholipid or one of several ester-linked phosph...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Derksen, J T, Baldeschwieler, J D, Scherphof, G L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282862/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3200855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9768
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