Differential effects of IL-2 and IL-21 on expansion of the CD4(+)CD25(+)Foxp3(+) T regulatory cells with redundant roles in natural killer cell mediated antibody dependent cellular cytotoxicity in chronic lymphocytic leukemia

CD4(+) CD25(+) regulatory Tt cells are expanded in solid and hematological malignancies including chronic lymphocytic leukemia (CLL). Several cytokines and co-stimulatory molecules are required for generation, survival and maintenance of their suppressive effect. We and others have shown direct cyto...

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Autors principals: Gowda, Aruna, Ramanunni, Asha, Cheney, Carolyn, Rozewski, Darlene, Kindsvoge, Wayne, Lehman, Amy, Jarjoura, David, Caligiuri, Michael, Byrd, John C, Muthusamy, Natarajan
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828576/
https://ncbi.nlm.nih.gov/pubmed/20081380
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