Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment.
beta transgenic mice have a T-cell receptor beta-chain gene that is prematurely expressed on the surface of CD4- CD8- thymocytes and paired with an uncharacterized non-T-cell receptor alpha-chain polypeptide. The rearrangement of the T-cell receptor variable region gamma chain gene segment V gamma 4...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1988
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2974164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9729 |
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