Early expression of a T-cell receptor beta-chain transgene suppresses rearrangement of the V gamma 4 gene segment.

beta transgenic mice have a T-cell receptor beta-chain gene that is prematurely expressed on the surface of CD4- CD8- thymocytes and paired with an uncharacterized non-T-cell receptor alpha-chain polypeptide. The rearrangement of the T-cell receptor variable region gamma chain gene segment V gamma 4...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	von Boehmer, H, Bonneville, M, Ishida, I, Ryser, S, Lincoln, G, Smith, R T, Kishi, H, Scott, B, Kisielow, P, Tonegawa, S
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1988
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282851/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2974164/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.24.9729
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