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Cyclic Adenosine Monophosphate Response Element-Binding Protein Phosphorylation and Neuroprotection by 4-Phenyl-1-(4-Phenylbutyl) Piperidine (PPBP)

BACKGROUND: Previous studies show that the potent, prototypical σ(1)-receptor agonist 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) prevents cell death after oxygen-glucose deprivation (OGD) in primary cortical neuronal cultures. We tested the hypothesis that PPBP protects neurons by a mechanism invo...

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Autors principals: Yang, Sufang, Alkayed, Nabil J., Hurn, Patricia D., Kirsch, Jeffrey R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828492/
https://ncbi.nlm.nih.gov/pubmed/19224810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ane.0b013e318192442c
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