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Sigma Receptor Agonists Provide Neuroprotection In Vitro by Preserving bcl-2
BACKGROUND: Sigma (σ)-receptor agonists attenuate brain injury after experimental focal cerebral ischemia in several species. We tested the hypothesis that the potent, prototypical σ(1)-receptor agonist, 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP), protects neurons by a mechanism involving the anti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596726/ https://ncbi.nlm.nih.gov/pubmed/17456670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/01.ane.0000260267.71185.73 |
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