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A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression

BACKGROUND: The extracellular deposition of aggregated amyloid β-protein is a neuropathological manifestation of Alzheimer disease and Down syndrome. The Amyloid β-protein is derived from a group of larger differentially spliced proteins, the amyloid protein precursors (APP). Data suggests that the...

詳細記述

保存先:
書誌詳細
主要な著者: Vostrov, Alexander A, Taheny, Michael J, Izkhakov, Nerik, Quitschke, Wolfgang W
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828463/
https://ncbi.nlm.nih.gov/pubmed/20205906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-4
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