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A nuclear factor-binding domain in the 5'-untranslated region of the amyloid precursor protein promoter: Implications for the regulation of gene expression
BACKGROUND: The extracellular deposition of aggregated amyloid β-protein is a neuropathological manifestation of Alzheimer disease and Down syndrome. The Amyloid β-protein is derived from a group of larger differentially spliced proteins, the amyloid protein precursors (APP). Data suggests that the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828463/ https://ncbi.nlm.nih.gov/pubmed/20205906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-3-4 |
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