Computational identification of rare codons of Escherichia coli based on codon pairs preference

BACKGROUND: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exogenous protein, have been defined by gene engineering operations. Previous studies have confirmed the existence of codon p...

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Detalhes bibliográficos
Main Authors: Wu, Xianming, Wu, Songfeng, Li, Dong, Zhang, Jiyang, Hou, Lin, Ma, Jie, Liu, Wanlin, Ren, Daming, Zhu, Yunping, He, Fuchu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828438/
https://ncbi.nlm.nih.gov/pubmed/20109184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-61
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