Activated Ras alters lens and corneal development through induction of distinct downstream targets

BACKGROUND: Mammalian Ras genes regulate diverse cellular processes including proliferation and differentiation and are frequently mutated in human cancers. Tumor development in response to Ras activation varies between different tissues and the molecular basis for these variations are poorly unders...

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Main Authors: Burgess, Daniel, Zhang, Yan, Siefker, Ed, Vaca, Ryan, Kuracha, Murali R, Reneker, Lixing, Overbeek, Paul A, Govindarajan, Venkatesh
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828409/
https://ncbi.nlm.nih.gov/pubmed/20105280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-13
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