Activated Ras alters lens and corneal development through induction of distinct downstream targets

BACKGROUND: Mammalian Ras genes regulate diverse cellular processes including proliferation and differentiation and are frequently mutated in human cancers. Tumor development in response to Ras activation varies between different tissues and the molecular basis for these variations are poorly unders...

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Detalhes bibliográficos
Main Authors: Burgess, Daniel, Zhang, Yan, Siefker, Ed, Vaca, Ryan, Kuracha, Murali R, Reneker, Lixing, Overbeek, Paul A, Govindarajan, Venkatesh
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828409/
https://ncbi.nlm.nih.gov/pubmed/20105280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-13
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