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Spry1 and Spry2 Are Necessary for Lens Vesicle Separation and Corneal Differentiation

PURPOSE. The studies reported here were performed to analyze the roles of Sproutys (Sprys), downstream targets and negative feedback regulators of the fibroblast growth factor (FGF) signaling pathway, in lens and corneal differentiation. METHODS. Spry1 and -2 were conditionally deleted in the lens a...

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Detalhes bibliográficos
Main Authors: Kuracha, Murali R., Burgess, Daniel, Siefker, Ed, Cooper, Jake T., Licht, Jonathan D., Robinson, Michael L., Govindarajan, Venkatesh
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176024/
https://ncbi.nlm.nih.gov/pubmed/21743007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7531
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