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Primary Peripheral T Cells Become Susceptible to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin-Mediated Apoptosis in Vitro upon Activation and in the Presence of Dendritic Cells

Although the toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on T cells in vivo have been well characterized, attempts to reproduce these findings in vitro have not been successful. In the current study, we examined whether activation or the presence of dendritic cells (DCs) would make p...

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Autori principali: Singh, Narendra P., Nagarkatti, Mitzi, Nagarkatti, Prakash
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828294/
https://ncbi.nlm.nih.gov/pubmed/18334599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.043406
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