Defects Along the Th17 Differentiation Pathway Underlie Genetically Distinct Forms of the Hyper IgE Syndrome

BACKGROUND: The hyper IgE syndrome (HIES) is characterized by abscesses, eczema, recurrent infections, skeletal and connective tissue abnormalities, elevated serum IgE and diminished inflammatory responses. It exists as autosomal dominant (AD) and recessive (AR) forms that manifest common and distin...

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Détails bibliographiques
Auteurs principaux: Khatib, Shadi Al, Keles, Sevgi, Garcia-Lloret, Maria, Karakoc-Aydiner, Elif, Reisli, Ismail, Artac, Hasibe, Camcioglu, Yildiz, Cokugras, Haluk, Somer, Ayper, Kutukculer, Necil, Yilmaz, Mustafa, Ikinciogullari, Aydan, Yegin, Olcay, Yüksek, Mutlu, Genel, Ferah, Kucukosmanoglu, Ercan, Baki, Ali, Bahceciler, Nerin N, Rambhatla, Anupama, Nickerson, Derek W., McGhee, Sean, Barlan, Isil B, Chatila, Talal
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828264/
https://ncbi.nlm.nih.gov/pubmed/19577286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2009.05.004
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