DOCK8 Regulates STAT3 Activation and Promotes Th17 Cell Differentiation

BACKGROUND: The autosomal recessive hyper IgE syndrome (AR-HIES) due to Dedicator Of Cytokinesis 8 (DOCK8) deficiency shares clinical features with the autosomal dominant HIES (AD-HIES) due to Signal Transducer and Activator of Transcription 3 (STAT3) mutations, including recurrent infections and mu...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Keles, Sevgi, Charbonnier, Louis Marie, Kabaleeswaran, Venkataraman, Reisli, Ismail, Genel, Ferah, Gulez, Nesrin, Al-Herz, Waleed, Ramesh, Narayanaswamy, Perez-Atayde, Antonio, Eeder, Neslihan Karaca, Kutukculer, Necil, Wu, Hao, Geha, Raif S., Chatila, Talal A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5099100/
https://ncbi.nlm.nih.gov/pubmed/27350570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.04.023
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