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mAKAP compartmentalizes oxygen-dependent control of HIF-1α
Induction of the hypoxia inducible transcription factor 1α (HIF-1α) pathway occurs during ischemic insult as an adaptation to reduced intracellular oxygen. Enzymes of the protein ubiquitin machinery that signal the destruction or stabilization of HIF-1α tightly control this transcriptional response....
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828263/ https://ncbi.nlm.nih.gov/pubmed/19109240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000026 |
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