The protein kinase A anchoring protein mAKAP co-ordinates two integrated cAMP effector pathways

Cyclic adenosine 3′, 5′ monophosphate (cAMP) is a ubiquitous mediator of intracellular signalling events. It principally acts through stimulation of cAMP-dependent protein kinases (PKA)1, 2 but also activates certain ion-channels and guanine nucleotide exchange factors (Epacs)3. Metabolism of cAMP i...

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Hauptverfasser: Dodge-Kafka, Kimberly L., Soughayer, Joseph, Pare, Genevieve C., Carlisle Michel, Jennifer J., Langeberg, Lorene K., Kapiloff, Michael S., Scott, John D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636584/
https://ncbi.nlm.nih.gov/pubmed/16177794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03966
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