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Elevated mitochondrial superoxide contributes to enhanced chemoreflex in heart failure rabbits

Peripheral chemoreflex sensitivity is enhanced in both clinical and experimental chronic heart failure (CHF). Here we investigated the role of manganese superoxide dismutase (MnSOD), the SOD isoform specially targeted to mitochondria, and mitochondrial superoxide levels in the enhanced chemoreceptor...

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Detalhes bibliográficos
Main Authors: Ding, Yanfeng, Li, Yu-Long, Zimmerman, Matthew C., Schultz, Harold D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828171/
https://ncbi.nlm.nih.gov/pubmed/19923358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00629.2009
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