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Downregulation of carbon monoxide as well as nitric oxide contributes to peripheral chemoreflex hypersensitivity in heart failure rabbits

Peripheral chemoreflex sensitivity is potentiated in clinical and experimental chronic heart failure (CHF). Downregulation of nitric oxide (NO) synthase (NOS) in the carotid body (CB) is involved in this effect. However, it remains poorly understood whether carbon monoxide (CO) also contributes to t...

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Detalhes bibliográficos
Main Authors: Ding, Yanfeng, Li, Yu-Long, Schultz, Harold D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494830/
https://ncbi.nlm.nih.gov/pubmed/18356479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.01345.2007
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