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Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be
Motivation: The mutation of amino acids often impacts protein function and structure. Mutations without negative effect sustain evolutionary pressure. We study a particular aspect of structural robustness with respect to mutations: regular protein secondary structure and natively unstructured (intri...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828120/ https://ncbi.nlm.nih.gov/pubmed/20081223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq012 |
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