A Requirement for DICER to Maintain Full Promoter CpG Island Hypermethylation in Human Cancer Cells

Promoter hypermethylation is a prevalent phenomenon, found in virtually all cancer types studied thus far, and accounts for tumor suppressor gene silencing in the absence of genetic mutations. The mechanism behind the establishment and maintenance of such aberrant hypermethylation has been under int...

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Главные авторы: Ting, Angela H., Suzuki, Hiromu, Cope, Leslie, Schuebel, Kornel E., Lee, Byron H., Toyota, Minoru, Imai, Kohzoh, Shinomura, Yasuhisa, Tokino, Takashi, Baylin, Stephen B.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828041/
https://ncbi.nlm.nih.gov/pubmed/18413723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6405
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