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Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice
Many signaling pathways that contribute to tumorigenesis are also functional in pregnancy, although they are dysregulated in the former and tightly regulated in the latter. Transformation-related protein 53 (Trp53), which encodes p53, is a tumor suppressor gene whose mutation is strongly associated...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827950/ https://ncbi.nlm.nih.gov/pubmed/20124728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40051 |
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