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FKBP52 deficiency–conferred uterine progesterone resistance is genetic background and pregnancy stage specific
Immunophilin FKBP52 serves as a cochaperone to govern normal progesterone (P(4)) receptor (PR) function. Using Fkbp52(–/–) mice, we show intriguing aspects of uterine P(4)/PR signaling during pregnancy. Implantation failure is the major phenotype found in these null females, which is conserved on bo...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1888571/ https://ncbi.nlm.nih.gov/pubmed/17571166 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI31622 |
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