Separating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation

Routine methods to maximize the graft-versus-leukemia (GvL) activity of allogeneic hematopoietic stem cell transplantation (HSCT) without the detrimental effects of graft-versus-host disease (GvHD) are lacking. Depletion or inhibition of alloreactive T cells is partially effective in preventing GvHD...

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Main Authors: Li, Jian-Ming, Giver, Cynthia R, Lu, Ying, Hossain, Mohammad S, Akhtari, Mojtaba, Waller, Edmund K
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827928/
https://ncbi.nlm.nih.gov/pubmed/20191089
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