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Purification and characterization of other distinct bone-inducing factors.

We purified a factor that induces bone formation greater than 300,000-fold from guanidinium chloride extracts of demineralized bone. Fifty nanograms of highly purified protein was active in an in vivo cartilage and bone-formation assay. The activity resided in a single gel band, corresponding to a m...

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Autors principals: Wang, E A, Rosen, V, Cordes, P, Hewick, R M, Kriz, M J, Luxenberg, D P, Sibley, B S, Wozney, J M
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC282777/
https://ncbi.nlm.nih.gov/pubmed/3200834
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