Recombinant human bone morphogenetic protein induces bone formation.

We have purified and characterized active recombinant human bone morphogenetic protein (BMP) 2A. Implantation of the recombinant protein in rats showed that a single BMP can induce bone formation in vivo. A dose-response and time-course study using the rat ectopic bone formation assay revealed that...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wang, E A, Rosen, V, D'Alessandro, J S, Bauduy, M, Cordes, P, Harada, T, Israel, D I, Hewick, R M, Kerns, K M, LaPan, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2315314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2220
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