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SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation

Dysfunction of the ureter often leads to urine flow impairment from the kidney to the bladder, causing dilation of the ureter and/or renal pelvis. Six1 is a crucial regulator of renal development: mutations in human SIX1 cause branchio-oto-renal (BOR) syndrome and Six1(–/–) mice exhibit renal agenes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nie, Xuguang, Sun, Jianbo, Gordon, Ronald E., Cai, Chen-Leng, Xu, Pin-Xian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827686/
https://ncbi.nlm.nih.gov/pubmed/20110314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.045757
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