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Mechanisms of Nucleotide Trafficking during siRNA Delivery to Endothelial Cells using Perfluorocarbon Nanoemulsions

RNA interference (RNAi) is a useful in vitro research tool, but its application as a safe and effective therapeutic agent may benefit from improved understanding of mechanisms of exogenous siRNA delivery, including cell trafficking and sorting patterns. We report the development of a transfection re...

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Detalhes bibliográficos
Main Authors: Kaneda, Megan M., Sasaki, Yo, Lanza, Gregory M., Milbrandt, Jeffrey, Wickline, Samuel A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827659/
https://ncbi.nlm.nih.gov/pubmed/20092889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.01.006
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