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Interpreting the effect of vaccination on steady state infection in animals challenged with Simian Immunodeficiency Virus

A representative vaccinated macaque challenged with SIVmac251 establishes a persistent infection with a lower virus load, higher CTL frequencies, and much higher helper cell frequencies, than a representative control animal. The reasons for the difference are not fully understood. Here we interpret...

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Autors principals: Sergeev, R.A., Batorsky, R. E., Coffin, J.M., Rouzine, I.M.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827631/
https://ncbi.nlm.nih.gov/pubmed/20034499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2009.12.018
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