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Conformational Flexibility in the IgE-Fc(3-4) Revealed in Multiple Crystal Forms

The structure of the IgE-Fc(3-4) has been solved in three new crystal forms, providing 13 snapshots of the Fc conformation and revealing a diverse range of open-closed motions among subunit chains and dimers. A more detailed analysis of the open-to-closed motion of the IgE-Fc(3-4) was possible with...

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Detalhes bibliográficos
Main Authors: Wurzburg, Beth A., Jardetzky, Theodore S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827403/
https://ncbi.nlm.nih.gov/pubmed/19682998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.012
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