Guanosine 5'-monophosphate modulates gating of high-conductance Ca2+-activated K+ channels in vascular smooth muscle cells.

Ca2+-activated K+ channels (PKCa channels) account for the predominant K+ permeability of many types of smooth muscle cells. When activated, they oppose depolarization due to Na+ and Ca2+ channel activity. Several vasodilatory agents that increase intracellular cGMP levels (e.g., nitroprusside, aden...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Williams, D L, Katz, G M, Roy-Contancin, L, Reuben, J P
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848262/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9360
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