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Preparation of fluorescently-labeled amyloid-beta peptide assemblies: the effect of fluorophore conjugation on structure and function

Recent research has focused on soluble oligomeric assemblies of the 42 amino acid isoform of the amyloid-beta peptide (Aβ42) as the proximal cause of neuronal injury, synaptic loss, and the eventual dementia associated with Alzheimer’s disease (AD). While neurotoxicity, neuroinflammation, and defici...

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Autors principals: Jungbauer, L. M., Yu, C, Laxton, K. J., LaDu, M. J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827260/
https://ncbi.nlm.nih.gov/pubmed/19343729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.948
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