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Fetal hemoglobin synthesis in vivo: direct evidence for control at the level of erythroid progenitors.

To test directly whether the control of fetal hemoglobin (HbF) in the adult takes place at the level of erythroid progenitors or at the level of erythroblasts, we treated animals with high doses of erythropoietin and examined the effects of this manipulation on the globin gene programs of erythroid...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Umemura, T, Al-Khatti, A, Papayannopoulou, T, Stamatoyannopoulos, G
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282722/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9278
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