Fetal hemoglobin synthesis in vivo: direct evidence for control at the level of erythroid progenitors.
To test directly whether the control of fetal hemoglobin (HbF) in the adult takes place at the level of erythroid progenitors or at the level of erythroblasts, we treated animals with high doses of erythropoietin and examined the effects of this manipulation on the globin gene programs of erythroid...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282722/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2461566/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.9278 |
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