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Targeted Deletion of the γ-Adducin Gene (Add3) in Mice Reveals Differences in α-Adducin Interactions in Erythroid and Nonerythroid Cells
In red blood cells (RBCs) adducin heterotetramers localize to the spectrin-actin junction of the peripheral membrane skeleton. We previously reported that deletion of β-adducin results in osmotically fragile, microcytic RBCs and a phenotype of hereditary spherocytosis (HS). Notably, α-adducin was si...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827150/ https://ncbi.nlm.nih.gov/pubmed/19425068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.21427 |
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