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Modification of Loop 1 Affects the Nucleotide-Binding Properties of Myo1c, The Adaptation Motor in the Inner Ear

Myo1c is one of eight members of the mammalian myosin I family of actin-associated molecular motors. In stereocilia of the hair cells in the inner ear, Myo1c presumably serves as the adaptation motor, which regulates the opening and closing of transduction channels. Although there is conservation of...

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Detalhes bibliográficos
Main Authors: Adamek, Nancy, Lieto-Trivedi, Alena, Geeves, Michael A., Coluccio, Lynne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826812/
https://ncbi.nlm.nih.gov/pubmed/20039646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901803j
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