Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia

To determine whether gene expression profiling could improve outcome prediction in children with acute lymphoblastic leukemia (ALL) at high risk for relapse, we profiled pretreatment leukemic cells in 207 uniformly treated children with high-risk B-precursor ALL. A 38-gene expression classifier pred...

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Main Authors: Kang, Huining, Chen, I.-Ming, Wilson, Carla S., Bedrick, Edward J., Harvey, Richard C., Atlas, Susan R., Devidas, Meenakshi, Mullighan, Charles G., Wang, Xuefei, Murphy, Maurice, Ar, Kerem, Wharton, Walker, Borowitz, Michael J., Bowman, W. Paul, Bhojwani, Deepa, Carroll, William L., Camitta, Bruce M., Reaman, Gregory H., Smith, Malcolm A., Downing, James R., Hunger, Stephen P., Willman, Cheryl L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2010
Ábhair:
Lymphoid Neoplasia
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826761/
https://ncbi.nlm.nih.gov/pubmed/19880498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-218560
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