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Hyaluronan oligosaccharide treatment of chondrocytes stimulates expression of both HAS-2 and MMP-3, but by different signaling pathways
OBJECTIVE: Small hyaluronan oligosaccharides displace hyaluronan from the cell surface and induce cell signaling events. In articular chondrocytes this cell signaling is mediated by the hyaluronan receptor CD44 and includes stimulation of genes involved in matrix degradation such as matrix metallopr...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826598/ https://ncbi.nlm.nih.gov/pubmed/19874928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2009.10.007 |
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