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Mechanisms involved in enhancement of the expression and function of aggrecanases by hyaluronan oligosaccharides
OBJECTIVE: Small hyaluronan (HA) oligosaccharides serve as competitive receptor antagonists to displace HA from the cell surface and induce cell signaling events. In articular chondrocytes this cell signaling is mediated by the HA receptor CD44 and induces stimulation of genes involved in matrix deg...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3241893/ https://ncbi.nlm.nih.gov/pubmed/21905012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33329 |
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