Escape from Human Monoclonal Antibody Neutralization Affects In Vitro and In Vivo Fitness of Severe Acute Respiratory Syndrome Coronavirus

Background. Severe acute respiratory syndrome (SARS) emerged as a human disease in 2002. Detailed phylogenetic analysis and epidemiologic studies have suggested that the SARS coronavirus (SARS-CoV) originated from animals. The spike (S) glycoprotein has been identified as a major target of protectiv...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rockx, Barry, Donaldson, Eric, Frieman, Matthew, Sheahan, Timothy, Corti, Davide, Lanzavecchia, Antonio, Baric, Ralph S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The University of Chicago Press 2010
Schlagworte:
Major Articles and Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826557/
https://ncbi.nlm.nih.gov/pubmed/20144042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/651022
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge