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New cytochrome P450 mechanisms: implications for understanding molecular basis for drug toxicity at the level of the cytochrome
IMPORTANCE OF THE FIELD: Cytochrome (CYP) P450 is a collective name for a very large group of heme enzymes, which catalyze largely oxidative reactions, including those of pharmacological and toxicological importance. Their efficient operation requires coupling of specific electron donor and O2 consu...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826162/ https://ncbi.nlm.nih.gov/pubmed/19947890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425250903329095 |
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