Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2.

cDNA clones of the human TOP1 gene encoding DNA topoisomerase I (EC 5.99.1.2) have been obtained by immunochemical screening of phage lambda libraries expressing human cDNA segments, using rabbit antibodies raised against purified HeLa DNA topoisomerase I. Hybridization patterns between the cloned c...

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Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Juan, C C, Hwang, J L, Liu, A A, Whang-Peng, J, Knutsen, T, Huebner, K, Croce, C M, Zhang, H, Wang, J C, Liu, L F
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2848244/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.23.8910
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