Viral Sanctuaries during Highly Active Antiretroviral Therapy in a Nonhuman Primate Model for AIDS

Highly active antiretroviral therapy (HAART) enables long-term suppression of plasma HIV-1 loads in infected persons, but low-level virus persists and rebounds following cessation of therapy. During HAART, this virus resides in latently infected cells, such as resting CD4(+) T cells, and in other ce...

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Main Authors: North, Thomas W., Higgins, Joanne, Deere, Jesse D., Hayes, Timothy L., Villalobos, Andradi, Adamson, Lourdes, Shacklett, Barbara L., Schinazi, Raymond F., Luciw, Paul A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Pathogenesis and Immunity
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826073/
https://ncbi.nlm.nih.gov/pubmed/20032180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02356-09
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