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The DR1 and DR6 First Exons of Human Herpesvirus 6A Are Not Required for Virus Replication in Culture and Are Deleted in Virus Stocks That Replicate Well in T-Cell Lines

Human herpesvirus 6A (HHV-6A) and HHV-6B are lymphotropic viruses which replicate in cultured activated cord blood mononuclear cells (CBMCs) and in T-cell lines. Viral genomes are composed of 143-kb unique (U) sequences flanked by ∼8- to 10-kb left and right direct repeats, DR(L) and DR(R). We have...

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Detalhes bibliográficos
Main Authors: Borenstein, Ronen, Zeigerman, Haim, Frenkel, Niza
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826055/
https://ncbi.nlm.nih.gov/pubmed/20053742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01951-09
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