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T-cell activation is required for efficient replication of human herpesvirus 6.

We have investigated whether T-cell activation is required for the replication of the T-lymphotropic human herpesvirus 6. The virus did not replicate in quiescent peripheral blood lymphocytes but replicated efficiently following exposure of the cells to the polyclonal mitogen phytohemagglutinin (PHA...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Frenkel, N, Schirmer, E C, Katsafanas, G, June, C H
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2166835/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.9.4598-4602.1990
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