T-cell activation is required for efficient replication of human herpesvirus 6.

We have investigated whether T-cell activation is required for the replication of the T-lymphotropic human herpesvirus 6. The virus did not replicate in quiescent peripheral blood lymphocytes but replicated efficiently following exposure of the cells to the polyclonal mitogen phytohemagglutinin (PHA...

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Bibliographic Details
Main Authors: Frenkel, N, Schirmer, E C, Katsafanas, G, June, C H
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC247937/
https://ncbi.nlm.nih.gov/pubmed/2166835
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