Spread of a Chromosomal Cefixime-Resistant penA Gene among Different Neisseria gonorrhoeae Lineages

In Neisseria gonorrhoeae, the mosaic type of penA, which encodes penicillin-binding protein 2 (PBP 2), is associated with reduced susceptibility to oral cephalosporins. To investigate the relatedness of N. gonorrhoeae clinical isolates with reduced susceptibility, we sequenced the penA genes of 32 i...

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Bibliographic Details
Main Authors: Ohnishi, Makoto, Watanabe, Yuko, Ono, Emi, Takahashi, Chieko, Oya, Hitomi, Kuroki, Toshiro, Shimuta, Ken, Okazaki, Norio, Nakayama, Shu-ichi, Watanabe, Haruo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826007/
https://ncbi.nlm.nih.gov/pubmed/20028823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01010-09
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