GES-13, a β-Lactamase Variant Possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa

GES-13 β-lactamase, a novel GES variant possessing Lys-104 and Asn-170, was identified in Pseudomonas aeruginosa. bla(GES-13) was the single gene cassette of a class 1 integron probably located in the chromosome. GES-13 efficiently hydrolyzed broad-spectrum cephalosporins and aztreonam. Imipenem was...

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Hlavní autoři: Kotsakis, S. D., Papagiannitsis, C. C., Tzelepi, E., Legakis, N. J., Miriagou, V., Tzouvelekis, L. S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825989/
https://ncbi.nlm.nih.gov/pubmed/20065056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01561-09
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