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A Foreign Protein Incorporated on the Tip of T3 Pili in Lactococcus lactis Elicits Systemic and Mucosal Immunity

The use of Lactococcus lactis to deliver a chosen antigen to the mucosal surface has been shown to elicit an immune response in mice and is a possible method of vaccination in humans. The recent discovery on Gram-positive bacteria of pili that are covalently attached to the bacterial surface and the...

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Main Authors: Quigley, Bernard R., Hatkoff, Matthew, Thanassi, David G., Ouattara, Mahamoudou, Eichenbaum, Zehava, Scott, June R.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825955/
https://ncbi.nlm.nih.gov/pubmed/20028807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01037-09
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