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Enhanced Susceptibility to Acute Pneumococcal Otitis Media in Mice Deficient in Complement C1qa, Factor B, and Factor B/C2
To define the roles of specific complement activation pathways in host defense against Streptococcus pneumoniae in acute otitis media (AOM), we investigated the susceptibility to AOM in mice deficient in complement factor B and C2 (Bf/C2(−/)(−)), C1qa (C1qa(−/)(−)), and factor B (Bf(−)(/)(−)). Bacte...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2825922/ https://ncbi.nlm.nih.gov/pubmed/20065024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01012-09 |
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