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Role of the alternative and classical complement activation pathway in complement mediated killing against Streptococcus pneumoniae colony opacity variants during acute pneumococcal otitis media in mice

There is considerable evidence that phase variation among transparent and opaque colony phenotypes of Streptococcus pneumoniae (Spn) plays an important role in the pneumococcal adherence and invasion. The current study was designed to investigate the interactions of the opacity phenotype variants of...

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Autori principali: Li, Qian, Li, Yong Xing, Douthitt, Kelsey, Stahl, Gregory L., Thurman, Joshua M., Tong, Hua Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511655/
https://ncbi.nlm.nih.gov/pubmed/22975410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2012.08.002
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