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Toll-Like Receptor 4 Signaling Leads to Severe Fungal Infection Associated with Enhanced Proinflammatory Immunity and Impaired Expansion of Regulatory T Cells

Toll-like receptors (TLRs) present in innate immune cells recognize pathogen molecular patterns and influence immunity to control the host-parasite interaction. The objective of this study was to characterize the involvement of TLR4 in the innate and adaptive immunity to Paracoccidioides brasiliensi...

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Main Authors: Loures, Flávio V., Pina, Adriana, Felonato, Maíra, Araújo, Eliseu F., Leite, Katia R. M., Calich, Vera L. G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825906/
https://ncbi.nlm.nih.gov/pubmed/20008536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01198-09
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